This striking print sets the encounter of two women, the Virgin Mary and her cousin Elizabeth, exchanging intimate news of their respective pregnancies, in the midst of a crowded scene with both onlookers and people going about their business. Based on a fresco by Francesco Salviati painted for the oratorio of San Giovanni Decollato in Rome, the engraving's differences suggest it may have made use of an intermediate design which Ghisi could have acquired during his trip to Rome in the 1540's. The influential fresco was interpreted by two other early engravers, one the contemporary Bartolomeo Passaroti (in the reverse), the other by the next-generation Netherlandish engraver Jacob Matham.